Originally posted by RudeBoy
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For use in the high-vibration environment of a guitar amplifier, you need to mechanically support 1/16th inch PCB no further than every 2" to ensure it does not flex.
I would recommend 0.093" thick PCB, not 0.062" (1/16th). That lets you run support points out to about 3-4".
I would recommend plating up to a minimum of two ounce copper, and also designing for equal % coverage of top and bottom layers, as well as making straight runs of copper no longer than about 2" before taking a corner, whether the trace run needs it or not.
The most complex board I worked on was about 23" by 27" and had 20 layers. I've heard that an TI they once built 24 layer boards. This was back in the day of 16 pin TTL logic, and they brick-walled both sides of the board with chips. They soldered them by putting rosin-core solder ringlets on each pin of each IC, then dipping the whole board in boiling peanut oil to reflow the solder on each pin.
Yield was about 5% on a good day.
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